A greater degree of cardiac hypertrophy correlated negatively with the expression of MQC and UPRmt genes, including PAM16, TIMM17B, MFN2, DNM1L, PPARGC1, HTRA2, HSPA9, SPG7, TPCN1, TPCN2, MAP1LC3A, BECN1, BNIP3, PARL, and PINK1. The gene discussed is TIMM17B; the disease is cardiac hypertrophy.