A greater degree of cardiac hypertrophy correlated negatively with the expression of MQC and UPRmt genes, including PAM16, TIMM17B, MFN2, DNM1L, PPARGC1, HTRA2, HSPA9, SPG7, TPCN1, TPCN2, MAP1LC3A, BECN1, BNIP3, PARL, and PINK1. This evidence concerns the gene TPCN1 and cardiac hypertrophy.