We also presented human in vitro evidence (Table 2) showing the upregulation of GLP-1 receptor expression in inflamed plaques of PsO patients compared to uninflamed areas and the skin of healthy controls [38] and the downregulation of inflammatory pathways upon the addition of GLP-1RAs in two in vitro studies utilizing FLS cultured from rheumatoid arthritis patients [39,40]. Here, GLP1R is linked to rheumatoid arthritis.