We assessed the expression of eight candidate genes—CD72, CHRDL2, HYAL1, IGFBP3, LRP11, SERPINH1, SPARCL1—across six scRNA-seq CRC datasets (GSE108989, GSE136394, GSE139555, GSE146771, EMTAB8107, and GSE166555). The gene discussed is IGFBP3; the disease is colorectal carcinoma.