IL6 and gallstones: In contrast, Tomoika [72] reported a CDOR (95% CI) of 0.012 (0.21–0.0007) with p = 0.005 in participants who had high levels of interleukin (IL)-6 and IL-33, while Takuma [74] reported a CDOR (95% CI) of 3.21 (169.56–0.06) in participants with histopathological findings such as hyperplastic changes (88%), as well as in those with the presence of hypertrophic muscular layers (63%), subserosa fibrosis (88%), adenomyomatosis (63%), gallstone (25%), Ki-67 labeling index (6%), and K-ras mutation (50%) (Table 4).