ADIPOQ and obesity due to melanocortin 4 receptor deficiency: miR-21 [54]: In order to study the role of inflammation, fibrosis and adiponectin in obesity-related kidney disease, Morrison MC et al. fed a human CRP transgenic (huCRPtg) mouse model with a C57BL/6J background with an NC diet or an HFD for 50 weeks, and also evaluated the effects of rosiglitazone and rosuvastatin based on their anti-inflammatory effects.