NPRL3 and epilepsy: Favourable epilepsy surgical outcomes have been reported in patients with GATOR-related epilepsies who underwent resective surgery (where 80% of patients achieved a good surgical outcome, Engel I or II) and modern surgical techniques such as laser interstitial thermal ablation allow removal of multiple epileptic foci and have already shown promise in a case of epilepsy with variable foci due to an NPRL3 mutation [182].