PNLIP and cancer: Interestingly, PTL and its analogs were shown to sensitize cancer cells to the effects of microtubule-targeting agents frequently used in chemotherapy, such as taxanes and vinca alkaloids (Liu et al, 2008; Shanmugam et al, 2006; Shanmugam et al, 2010; Sweeney et al, 2005; Zhang et al, 2009).