IER3IP1 is associated with brain development and, when mutated, gives rise to developmental abnormalities including Microcephaly Epilepsy Diabetes syndrome (MEDS) (Abdel-Salam et al, 2012; Shalev et al, 2014; Poulton et al, 2011). This evidence concerns the gene IER3IP1 and microcephaly, epilepsy, and diabetes syndrome.