In this context, this study aimed to investigate the seminal plasma and serum expression of TUG1, MALAT1, miR-483, and miR-141 and their networks TGF-β1 and STAT3 in infertile men with non-obstructive azoospermia (NOA) and severe oligozoospermia (SO). This evidence concerns the gene STAT3 and Infertility.