PAFAH1B3 and neoplasm: Most interestingly, even three tumor lipases, ABHD12, FAAH2, and PAFAH1B3, which are associated with patient low life expectancy within discriminative signature, showed statistically significant correlations of their catalytic fractions with the tumor concentration of the divalent metal ions As, Se, and Cr, respectively (ABHD12 and As: rho=0.64, p = 0.03; FAAH2 and Se: rho = 0.67, p = 0.024; PAFAH1B3 and Cr: rho = 0.063, p = 0.04; Fig. 7a).