The median HGB, absolute reticulocyte count(Ret), and lactate dehydrogenase of PNH patients were 76(37–116)g/L, 181.0(45.9–495.8)×109/L, and 1 875(377–5 509)U/L, respectively. This evidence concerns the gene CYGB and paroxysmal nocturnal hemoglobinuria.