Analysis of available RNAseq (INRP000146) data for uninfected, LD-S and LD-R-infected-PEC (Figure 6A) revealed a suppression of Npc1 expression along with its transcription factor Srebp2 (Garver et al., 2008), in response to LD-R-infection. The gene discussed is SREBF2; the disease is infection.