IQR: interquartile range; Control: Healthy volunteers; GD: Graves’ disease; GO: Graves’ orbitopathy; FT3: Free Triiodothyronine; FT4: Free Thyroxine; TSH: Thyroid-stimulating hormone; TRAb: thyrotropin Receptor Antibodies. The gene discussed is TSHR; the disease is Graves ophthalmopathy.