Interestingly, bronchoalveolar lavage (BAL) from women with SSc-ILD exhibited increased concentration of proinflammatory mediators (G-CSF, IL-12), whereas BAL from men with SSc-ILD exhibited increased concentrations of profibrotic mediators (MMP-13, TIMP 1) [59]. The gene discussed is MMP13; the disease is systemic sclerosis.