In cerebrospinal fluid analysis, increased total Tau levels and a predominance of the 3R-Tau isoform have been observed, which helps differentiate it from other tauopathies such as Progressive Supranuclear Palsy (PSP) or Corticobasal Degeneration (CBD) [77]. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.