[140] and exhibited the strongest inhibitory activity against 16 cancer-related protein kinases, including aurora-B, PIM1, and VEGF-R2 with IC50 values ranging from 0.40 to 74.0 μmol/L, against these three protein kinases with IC50 values ranging from 0.3 to 11.7 μmol/L [141], and non-specific antioxidant effects with IC50 values greater than 200 μmol/L [140]. Here, WEE1 is linked to cancer.