TNF and periodontitis: A recent study by de Olivera et al. [192] on an animal model evaluated the effects of a moderate-intensity physical training protocol on ABL in rats with ligature-induced periodontitis; in addition, the authors evaluated inflammatory cytokines such as IL-1β, IL-6, TNF-α, and IL-10; C-reactive protein; lipid peroxidation (LPO); and reduced glutathione using histological and microtomographic evaluation.