TLR4 and infection: We also speculate that miR-8 targets the AcMNPV-EGFP genes at the early stage of AcMNPV-EGFP infection to inhibit the proliferation of the virus, while miR-8 inhibits the proliferation of AcMNPV-EGFP by regulating the Toll signaling pathway to increase the expression of AMPs at the late stage of infection.