HDAC11 negatively regulated the expression of interleukin-13/17 (IL-13/17) and tumor necrosis factor-alpha (TNF-α) in Hodgkin lymphoma, suggesting that HDAC11 inhibitors killed tumor cells by activating inflammatory responses, immune system activity, and apoptosis processes (Buglio et al., 2011). Here, TNF is linked to Hodgkins lymphoma.