SAA1 and coronary artery disorder: Chen et al. (2020) reported an association between the genetic locus polymorphisms of SAA1 and coronary artery disease in KD, indicating that SAA1 may be involved in the process of coronary artery injury. Increased levels of SAA1 protein in human periodontal lesion tissues are positively correlated with periodontal inflammation, and SAA1 may induce inflammatory cell infiltration and release inflammatory factors through toll-like receptor two and toll-like receptor 4 (Hirai et al., 2019).