Such proteins include: A(, α-synuclein, TDP-43 (TAR DNA-binding protein 43), FUS (fused in sarcoma), Huntingtin, and p53 which each form aggregates associated, respectively, with Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS)/ frontotemporal degeneration (FTD), Huntington’s, and cancer 2, 3, 4. Here, TARDBP is linked to Parkinson disease.