KEGG pathway enrichment analysis identified 161 significant pathways (Figure 1E), including the AGE-RAGE signaling pathway in diabetic complications, endocrine resistance, progesterone-mediated oocyte maturation, lipid metabolism and atherosclerosis, Kaposi sarcoma-associated herpesvirus infection, neurotrophin signaling pathway, VEGF signaling pathway, cellular senescence, Yersinia infection, and prolactin signaling pathway. Here, VEGFA is linked to atherosclerosis.