TFRC and Alzheimer disease: Transferrin receptor-targeted liposomes carrying Ferrostatin-1 can mediate transport across the blood–brain barrier via TfR on the surface of brain capillary endothelial cells, reducing the accumulation of lipid peroxides; exosome-Liproxstatin-1 complexes utilize the natural targeting ability of bone marrow mesenchymal stem cell exosomes, preferentially enriching around Aβ plaques in AD models, increasing the survival rate of hippocampal neurons.