MiR-21-3p associated with TRL signaling, and B-cell activated factor signaling, and miR-487b-3p associated with role of JAK2 in hormone-like cytokine signaling, histamine degradation, and IL-9 signaling; both miRs were associated with cancer. miR-487-3p and miR-21-3p were associated with inflammatory disease and dermatological diseases, respectively. This evidence concerns the gene JAK2 and cancer.