Huang et al. [31] found that baicalin suppressed the expression of glycolytic enzymes hexokinase 2 (HK2), phosphofructokinase 1 (PFK1), and pyruvate kinase muscle 2 (PKM2) to inhibit glucose metabolism in tumor cells, thereby impeding the growth and function of melanoma tumors. The gene discussed is HK2; the disease is neoplasm.