Additionally, while serum CXCL12 levels were elevated in bothDec1+/+ andDec1−/− tumor-bearing mice compared with their respective controls,Dec1+/+-4T1 mice exhibited significantly higher CXCL12 levels thanDec1−/−-4T1 mice (Fig. 9B). The gene discussed is CXCL12; the disease is neoplasm.