In other cancers, BARD1 (40), RAD51D (38),RAD54L (36), BRCA1 (34.5), MRE11 (34), WRN (33), GEN1 (33), FANCD2 (31), and BLM (30.5) showed higher HRD scores. The HRD scores for BRCA1 or BRCA2 were not significantly higher than other oHRR biallelic losses, consistent with the findings in Fig. 3A, indicating the possible influence of sample sizes and other factors in other cancers. The gene discussed is BLM; the disease is cancer.