Furthermore, this study screens active substances such as Kaempferol, Norephedrine, Cynaroside, Genistein, and Rutin, which can target critical proteins including AKT1, TNF, IL1B, EGFR, IFNG, IL4, CASP3, and PTGS2, to function significantly in the pathogenesis of asthma. This evidence concerns the gene IL4 and asthma.