CCL2 and cancer: Another polyphenol of the catechin family, the epigallocatechin gallate (EGCG), found in green tea plants (Camellia sinensis) and skins of some fruits and vegetables, demonstrates a crucial anti-inflammatory response through the inhibition of immune cell recruitment and activation, decreasing of pro-inflammatory cytokines releasing (TNF-α, IL-6, IL-8, IL-1β, MCP-1, and MMPs), and reducing reactive species generating (ROS and RNS) mainly regulated by modulation several pathways implicated in inflammation-induced cancer [364, 367].