Constitutive MMP-2 and MCP-1 secretions tended to decrease in the BBB and all cell types, although, interestingly, Mtb/VSV-G pseudotyped HIV-1 co-infection induced an increase of MMP-2 concentration in microglia (3.1- and 6.2-fold increase compared to uninfected and Mtb mono-infected conditions, respectively). This evidence concerns the gene MMP2 and coinfection.