Among them, pancreatic necrosis area > 50% (P = .004), systemic inflammatory response syndrome (P = .029), acute respiratory distress syndrome (P = .002), shock (P = .007), OF (P < .001), multiple organ failure (P < .001), POF (P < .001), respiratory failure (P = .003), cardiovascular failure (P = .009), renal failure (P = .004), extrapancreatic infection (P = .008), intensive care unit stay (P < .001), APACHE II score (P = .004), white blood cell account (P = .018), C-reactive protein account (P = .030), and PCT account (P = .006) were statistically significant. This evidence concerns the gene CRP and kidney failure.