CALCA and bacterial infectious disease: Cholangitis due to biliary obstruction could be excluded, although local bacterial infections usually do not increase the serum PCT level above the 0.5 ng/mL sepsis cutoff.[19] Despite moderate leukopenia and moderate thrombocytopenia (Table 1), the patient had no fever or other signs or symptoms of sepsis or septic shock.[8] In February 2022, after consultation with the patient and family, chemotherapy was discontinued and the patient was transferred to best supportive care.