Apigenin, the main constituent in wheatgrass, has been demonstrated to block lipopolysaccharide-induced lethality in vivo and proinflammatory cytokine expression by inactivating NF-κB through the suppression of p65 phosphorylation.[46] Moreover, the patients treated with wheatgrass juice experienced significant reductions in disease activity index and the severity of rectal bleeding.[25]. The gene discussed is NFKB1; the disease is Abnormal bleeding.