Expression of ROCK1 has been observed to be regulated by miRNAs in different cancers, such as miR-124 in colorectal cancer (15), miR-124-3p in bladder cancer (16), miR-135a in gastric cancer (17), miR-144 in sarcoma (18), miR-129-5p in osteosarcoma (19) miR-148a in non-small cell lung cancer (20), miR-150 in thyroid cancer (21), miR-196a-5p in nasopharyngeal carcinoma (22), miR-584-3p in glioma (23), miR-1280 in bladder cancer (24), and miR-186 in leukemia (25). The gene discussed is ROCK1; the disease is urinary bladder carcinoma.