In ROBO1-KO mice, the interneurons are found in the striatum due to the defects of neural migration.50,51ROBO1 has also been associated with neurodevelopmental disorders such as dyslexia52,53 and autism.54 In this study, we discovered that removing m6A modifications in ROBO1 mRNAs by dCas13 system leads to the downregulation of neural differentiation-related genes (Supplementary Figure S9). This evidence concerns the gene ROBO1 and neurodevelopmental disorder.