Additionally, C18:0—Cer correlated positively with serum pro—inflammatory cytokines (IL—1β, IL—6, IL— 17 A, IL—21) and the proportion of circulating memory B cells, suggesting it may contribute to MG pathogenesis by modulating the Th17/Treg balance, promoting inflammation, and activating B cells. Here, IL1B is linked to myasthenia gravis.