SLC7A11 and cancer: SLC7A11 promotes the synthesis of cysteine from extracellular cystine, which is primarily required for tumor cells.46 Moreover, SLC7A11 participates in regulating glucose metabolism and the TCA cycle, supporting cancer cell survival and distant metastasis.47,48 Results of the present study revealed that SLC7A11 overexpression promoted the release of GSH and suppressed oxidative stress.