2024). Additionally, verbascoside was reported as the PPARA ligand, and its good anti‐inflammatory activity was diminished in PPARA knockout mice (Esposito et al. 2010). This study found that verbascoside from Rehmanniae Radix Praeparata regulated PPARA transcriptional regulatory networks and enhanced glucose consumption in HepG2 cells. These results elucidate the underlying mechanisms of verbascoside and Rehmanniae Radix Praeparata for treating diabetic nephropathy. The anti‐diabetic nephropathy common mechanism of ZGP and YGP is summarized in Figure 7. Here, PPARA is linked to diabetic kidney disease.