Therefore, anti-IgE therapies are effective in alleviating clinical symptoms in children, minimizing the number of acute asthma flare-ups, reducing the need for oral medications, and enhancing quality of life, asthma symptoms, eosinophilic inflammation, and airway remodeling, as well as have a significant effect on asthma-associated allergic diseases [10,11]. This evidence concerns the gene IGHE and asthma.