Primary prevention strategies, such as the administration of pegfilgrastim (peg-G-CSF), are selected by therapists or patients based on specific chemotherapy regimens or significant risk factors for severe CIN (Li et al., 2017), and some other adjuvant drugs are commonly utilized to prevent vomiting or hepatic compromise in all chemo-supportive protocols. Here, CSF3 is linked to cervical squamous intraepithelial neoplasia.