We identified 11 distinct loci harboring multiple genes significantly associated with AF risk (p < 0.05), including CEP68 (2p14), FKBP7 (2q31), SPATS2L (2q33.1), UBE2D3 (4q24), CAMK2D (4q26), SLC2A9 (4p16.1), SHROOM3 (2q31.2), CCDC158 (4q21.1), CCNT2, RPL9, and FBXL5 (Table S4). This evidence concerns the gene CAMK2D and atrial fibrillation.