For further exploring the role of FGFBP2+ NK cell in HCC progression, the pseudo-time trajectory of FGFBP2+ NK cell from normal to HCC was constructed by Monocle2, and the branch with more healthy samples was set as the starting point, and the branch with more HCC samples was set as the ending point (Figs. 3A and 3B). Here, FGFBP2 is linked to hepatocellular carcinoma.