Considering that a number of genes in the list have an inhibitory effect on the processes of antigen presentation and cytotoxicity (CLEC2D, ICOSLG, MC1R, RNFT2, SPINK5, TMEM176B, UBASH3A), one can assume that in a number of patients with schizophrenia, their functionally significant SNPs contribute to the chronicity of infections, systemic inflammation, as well as autoimmune reactions and damage to their own cells. The gene discussed is ICOSLG; the disease is infection.