ICOSLG and schizophrenia: Considering that a number of genes in the list have an inhibitory effect on the processes of antigen presentation and cytotoxicity (CLEC2D, ICOSLG, MC1R, RNFT2, SPINK5, TMEM176B, UBASH3A), one can assume that in a number of patients with schizophrenia, their functionally significant SNPs contribute to the chronicity of infections, systemic inflammation, as well as autoimmune reactions and damage to their own cells.