FOXC1 is stabilized by OGT-mediated O-GlcNAcylation in liquid condensates to serve as a transcriptional activator of ASNS and GPT2, thereby increasing intracellular asparagine and alanine biogenesis, which enhances the ability of NB cells to resist ferroptosis, as well as promotes their growth, invasion, and metastasis. Here, OGT is linked to neuroblastoma.