Asparagine and alanine deprivation abolished the elevation in GSH/GSSG ratio, GPX4 activity, or NADPH/NADP+ ratio, reduction in lipid ROS levels, and increase in mitochondrial membrane potential, proliferation, and invasion of NB cells exhibiting excessive expression of FOXC1 (Fig. S2A to G). The gene discussed is FOXC1; the disease is neuroblastoma.