The objectives of the study were to collate serum MG-53 levels between ACS patients and healthy controls, to analyze the thrombolysis in myocardial infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) scores and Killip classes for ACS severity and to determine the association between serum MG-53 level; traditional cardiac markers, i.e., CK-MB, troponin-I, and heart-type fatty acid binding protein (H-FABP); and various risk scores of ACS. Here, FABP3 is linked to myocardial infarction.