SS shows a specific chromosomal translocation, t(X;18;p11;q11), resulting in the formation of an oncogenic fusion gene, usually either SS18(SYT)::SSX1 or SS18::SSX2 and rarely SS18::SSX4 [1]. So far, there is no evidence of any correlation between the different fusion partners (SSX1, SSX2, and SSX4) and SS tumor morphology. The gene discussed is SSX4; the disease is synovial sarcoma.