Additionally, SUA can inhibit adiponectin synthesis in adipocytes by reducing nitric oxide production in arterial endothelial cells, disrupting the tricarboxylic acid cycle and fatty acid β‐oxidation, and promoting cellular oxidative activity [40], which reduce the decomposition of serum triglycerides, leading to the higher incidence of hypertriglyceridemia in participants with high SUA levels. This evidence concerns the gene ADIPOQ and hypertriglyceridemia.