Conversely, non-Th2 endotype, or non- eosinophilic asthma, encompassing neutrophilic asthma mediated through IL-6/IL-17-driven Th1/Th17 pathways and paucigranulocytic asthma in which neither eosinophils nor neutrophils are increased (Tliba and Panettieri, 2019; Hammad and Lambrecht, 2021). Here, IL17A is linked to asthma.