Current diagnostic approaches primarily rely on tuberculin skin tests (TST, Diaskintest, C-Tb, EC-test) and interferon-gamma release assays (IGRAs: T-SPOT.TB, QFT-GIT, QFT-Plus, LIASON QFT-Plus, LIOFeron TB/LTBI) (Gong and Wu, 2021; Li et al., 2024; Li et al., 2023). The gene discussed is IFNG; the disease is tuberculosis.