It may promote the production of inflammatory factors such as IL-6 and TNF-α, which may lead to renal dysfunction, including glomerular endothelial cell damage, vascular smooth muscle cell proliferation, andRenin-Angiotensin-Aldosterone System (RAAS) activation (Mironova, 2023; Zhang et al., 2023). This evidence concerns the gene IL6 and Abnormal renal physiology.